Highly regioselective osmium-catalyzed hydroformylation.

نویسندگان

  • Lipeng Wu
  • Qiang Liu
  • Anke Spannenberg
  • Ralf Jackstell
  • Matthias Beller
چکیده

The first highly regioselective and general osmium-catalyzed hydroformylation of olefins to aldehydes is reported. The combination of Os3(CO)12 and imidazoyl-substituted phosphine ligands allows n-selective (up to 99%) hydroformylation of bulk aliphatic as well as functional alkenes in good yields (64-87%).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Disulfide catalyzed the highly regioselective conversion of epoxides to halohydrins with elemental halogens

The regioselective ring opening of styrene oxide using elemental iodine and bromine in the presence of disulfides as new catalysts was studied. The conductivity titration and UV spectroscopy were used to study the interaction of iodine with these catalysts. The results indicate that disulfide 11 is efficient in polyiodide formation, and can catalyze this reaction in excellent yield and high reg...

متن کامل

CHEMOSELECTIVITY AND REGIOSELECTIVITY IN HYDROFORMYLATION The control of chemoselectivity is a fundamental concern in Rh-catalyzed hydroformylation

1 RHODIUM-CATALYZED STEREOSELECTIVE HYDROFORMYLATION Reported by Daniel Robbins October 16, 2008 INTRODUCTION Hydroformylation, the conversion of olefins into aldehydes through the addition of CO and H2, is an important industrial reaction that employs homogeneous catalysis by transition metals (Figure 1). Hydroformylation is a valuable reaction in organic chemistry because it produces aldehyde...

متن کامل

Disulfide catalyzed the highly regioselective conversion of epoxides to halohydrins with elemental halogens

The regioselective ring opening of styrene oxide using elemental iodine and bromine in the presence of disulfides as new catalysts was studied. The conductivity titration and UV spectroscopy were used to study the interaction of iodine with these catalysts. The results indicate that disulfide 11 is efficient in polyiodide formation, and can catalyze this reaction in excellent yield and high reg...

متن کامل

Synthesis of (-)-Indolizidine 167B based on domino hydroformylation/cyclization reactions

The synthesis of (-)-Indolizidine 167B has been achieved from optically active (R)-3-(pyrrol-1-yl)hex-1-ene. The key step is a highly regioselective hydroformylation reaction and a one-pot intramolecular cyclization providing a general approach to the indolizine nucleus.

متن کامل

One-pot synthesis of highly regioselective β-azido alcohols catalyzed by Brønsted acidic ionic liquids

In this protocol, 3-(2-carboxybenzoyl)-1-methyl-1H-imidazol-3-ium chloride [Cbmim]Cl and sulfonic acid functionalized pyridinium chloride [pyridine-SO3H]Cl as a new, reusable, and green Brønsted acidic ionic liquid (BAIL) catalyst were synthesized and successfully used for the one-pot ring opening of epoxide with sodium azide (NaN3) in water at room temperature. Epoxides under ring-opening easi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 51 15  شماره 

صفحات  -

تاریخ انتشار 2015